OnCall Doctors: Private Healthcare for Lancashire and the Fylde Coast
Make an appointment today on 01253 834055

Enter any discussion on weight loss injections UK, and you’ll always hear these three names: Mounjaro, Wegovy, and Saxenda. They are all prescription-only medications. And they are all authorised for weight management. But there are other significant differences between them, and the choice between these products requires a more comprehensive study than just googling it.
| Treatment | Active Ingredient | How It Works | How Often |
| Mounjaro | Tirzepatide | Targets GLP-1 and GIP | Once weekly |
| Wegovy | Semaglutide | Targets GLP-1 | Once weekly |
| Saxenda | Liraglutide | Targets GLP-1 | Once daily |
Each one functions by reducing the urge for food and assisting in weight loss by mimicking hormones that regulate hunger and blood glucose levels, including GLP-1 injections. The only difference is that Mounjaro targets two receptors, while other medications target just one.
Mounjaro is an artificial hormone that acts on GLP-1 and GIP receptors. The first one inhibits stomach emptying and creates a sensation of satiety, while the second one stimulates fat burning and prevents fat storage. The effect of the drug is more powerful than drugs with only one receptor, as shown in clinical trials when higher doses were tested, making Mounjaro vs Wegovy a relevant consideration.
Wegovy acts solely on GLP-1; it produces similar results to Mounjaro when used in large amounts. The unique feature about Wegovy, however, is that it has been licensed in the UK to reduce the risks of developing heart attacks and strokes among people suffering from pre-existing cardiovascular disorders and being overweight. This indication is especially significant for patients with pre-existing heart conditions.
Unlike other new medications, Saxenda (liraglutide) has to be administered daily instead of weekly weight loss injections in the UK. Its weight loss effects are relatively lower. However, Saxenda is a licensed product, and for some patients, it may be a good fit when considering private prescriptions for weight management.
Ozempic contains semaglutide; however, its use for weight loss is not indicated in the United Kingdom. Ozempic is not recommended in the United Kingdom because of the restricted availability of the drug for diabetic patients.
The criteria used here are that either BMI must be 30 or more, or, in the case of BMI being 27 or more, there must be some health issue related to obesity. There are lower BMI criteria specified by NICE for certain ethnic groups as per their higher metabolic risks and obesity treatment requirements.
OnCall Doctors is a GP run private clinic situated on the Fylde Coast of Lancashire, which provides consultations for Mounjaro, Wegovy, and other prescription medications for weight management, including weight loss injections UK. With more than 20 years of medical practice under their belts, both in the NHS and in the private sector, OnCall Doctors make an informed clinical assessment before prescribing any kind of medication. More time with your GP can support a more detailed consultation when treatment options need to be considered.